HDAC6-IN-19

MedChem Express

HDAC6-IN-19

14

Research Use Only

C26H23ClN4O3

474.94

HDAC6-IN-19 (Compound 14g) is a HDAC6 inhibitor (IC50: 2.68 nM). HDAC6-IN-19 also inhibits HDAC1, HDAC2 and HDAC3 with IC50s of 61.6 nM, 98.7 nM and 103 nM. HDAC6-IN-19 potently inhibits multiple cancer cell proliferation, including leukemia, colon cancer, melanoma, and breast cancer cell lines[1].

O=C([C@H]1CC2=C([C@H](C3=CC=C(Cl)C=C3)N1)NC4=C2C=CC=C4)NCC5=CC=C(C(NO)=O)C=C5

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