HDAC6-IN-8 [2796282-49-8]

MedChem Express

HDAC6-IN-8 [2796282-49-8]

10

2796282-49-8

Research Use Only

C23H17BrFN5O3

510.32

A variety of compounds were designed and synthesized by modifying cap groups. The enzyme inhibition test showed that compound 12C had broad-spectrum enzyme inhibitory activity, and compounds 9m and 9q were more inclined to inhibit HDAC6, showing a certain selective inhibitory activity among the representative subtypes.

O=C(NC1=CC=C2N=CN=C(C2=C1)NC3=CC(F)=C(C=C3)Br)CC4=CC=C(C=C4)C(NO)=O

12131703