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Heneicosapentaenoic acid

HY-N7833
MedChem Express
CAS Number24257-10-1
Product group Chemicals
Molecular Weight316.48
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Overview

  • Supplier
    MedChem Express
  • Product Name
    Heneicosapentaenoic acid [24257-10-1]
  • Delivery Days Customer
    10
  • CAS Number
    24257-10-1
  • Molecular Formula
    C21H32O2
  • Molecular Weight
    316.48
  • Scientific Description
    Heneicosapentaenoic Acid (HPA) is a 21:5 omega-3 fatty acid found in trace amounts in the green alga B. pennata and in fish oils. Its chemical composition is similar to eicosapentaenoic acid (EPA), except that a carbon is extended at the carboxy terminus, placing the first double bond at the delta6 position. HPA can be used to study the importance of double bond position in omega-3 fatty acids. It incorporates phospholipids and triacylglycerols in vivo with the same efficiency as EPA and docosahexaenoic acid, and exhibits a strong inhibitory effect on the synthesis of arachidonic acid from linoleic acid. HPA is a poor substrate for prostaglandin H synthase (PGHS) (cyclooxygenase) and 5-lipoxygenase, but retains the ability to rapidly inactivate PGHS.
  • SMILES
    CC/C=C\C/C=C\C/C=C\C/C=C\C/C=C\CCCCC(O)=O
  • UNSPSC
    12352200