Hepatitis C virus NS3 protein antibody [113]

GeneTex

Hepatitis C Virus NS3 protein antibody [113]

9

GTX18664 reacts with recombinant NS-3 (1252aa-1477aa), synthetic NS-3 (1378aa-1458aa), and recombinant chimeric HCV polyprotein (60 kDa). No cross reaction can be seen with recombinant CPC* + EPM** (core) (amino acids 1-142), synthetic CPC* (amino acids 1

ELISA: Use at an assay dependent dilution. WB: Use at a concentration of 0.1 - 1 microg/ml. Predicted molecular weight: 60 kDa. Optimal dilutions/concentrations should be determined by the end user. GTX18664 will allow visualization of 100 ng/lane of both recombinant chimeric HCV polyprotein and recombinant NS-3 Protein. No reaction is seen with synthetic NS-3.

Western Blot, ELISA

Research Use Only

Monoclonal

113

1 mg/ml

Unconjugated

Liquid

Mouse

IgG1

HCV is a positive, single-stranded RNA virus in the Flaviviridae family. The genome is approximately 10,000 nucleotides and encodes a single polyprotein of about 3,000 amino acids. The polyprotein is processed by host cell and viral proteases into three major structural proteins and several non-structural proteins necessary for viral replication. Several different genotypes of HCV with slightly different genomic sequences have since been identified that correlate with differences in response to treatment with interferon alpha.

Virus

-20°C or -80°C,2°C to 8°C

12352203