HER2/CD340, Mouse (HEK293, His)

MedChem Express

HER2/CD340, Mouse (HEK293, His)

10

Research Use Only

95.0

Erbb2

erb-b2 receptor tyrosine kinase 2

Erbb-2, HER-2, HER2, Neu, c-erbB2, c-neu, l11Jus8, mKIAA3023, receptor tyrosine-protein kinase erbB-2, Neu oncogene, avian erythroblastosis oncogene B 2, c-erbB-2, p185erbB2, proto-oncogene NEU, proto-oncogene c-ErbB-2, v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog

Receptor tyrosine-protein kinase erbB-2

The HER2/CD340 protein is a multifunctional tyrosine kinase that is a component of the neuregulin receptor complex and regulates microtubule dynamics. Activated HER2/CD340 triggers the MEMO1-RHOA-DIAPH1 pathway, inhibits GSK3B on the cell membrane and promotes the binding of APC and CLASP2, which is critical for microtubule stability. HER2/CD340 Protein, Mouse (HEK293, His) is the recombinant mouse-derived HER2/CD340 protein, expressed by HEK293 , with C-10*His labeled tag.

-20°C

41116100