
Whole cell extract (30 μg) was separated by 5% SDS-PAGE, and the membrane was blotted with HERC5 antibody (GTX130167) diluted at 1:1000.
HERC5 antibody
GTX130167
ApplicationsWestern Blot
Product group Antibodies
ReactivityHuman
TargetHERC5
Overview
- SupplierGeneTex
- Product NameHERC5 antibody
- Delivery Days Customer9
- Application Supplier NoteWB: 1:500-1:3000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
- ApplicationsWestern Blot
- CertificationResearch Use Only
- ClonalityPolyclonal
- Concentration3.96 mg/ml
- ConjugateUnconjugated
- Gene ID51191
- Target nameHERC5
- Target descriptionHECT and RLD domain containing E3 ubiquitin protein ligase 5
- Target synonymsCEB1, CEBP1, E3 ISG15--protein ligase HERC5, HECT domain and RCC1-like domain-containing protein 5, cyclin-E-binding protein 1, hect domain and RLD 5, probable E3 ubiquitin-protein ligase HERC5
- HostRabbit
- IsotypeIgG
- Protein IDQ9UII4
- Protein NameE3 ISG15--protein ligase HERC5
- Scientific DescriptionThis gene is a member of the HERC family of ubiquitin ligases and encodes a protein with a HECT domain and five RCC1 repeats. Pro-inflammatory cytokines upregulate expression of this gene in endothelial cells. The protein localizes to the cytoplasm and perinuclear region and functions as an interferon-induced E3 protein ligase that mediates ISGylation of protein targets. The gene lies in a cluster of HERC family genes on chromosome 4. [provided by RefSeq]
- ReactivityHuman
- Storage Instruction-20°C or -80°C,2°C to 8°C
- UNSPSC12352203
References
- Jin J, Meng X, Huo Y, et al. Induced TRIM21 ISGylation by IFN-β enhances p62 ubiquitination to prevent its autophagosome targeting. Cell Death Dis. 2021,12(7):697. doi: 10.1038/s41419-021-03989-xRead this paper






