HERC5 antibody
GTX130167
Overview
- SupplierGeneTex
- Product NameHERC5 antibody
- Delivery Days Customer9
- Application Supplier NoteWB: 1:500-1:3000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
- ApplicationsWestern Blot
- CertificationResearch Use Only
- ClonalityPolyclonal
- Concentration3.96 mg/ml
- ConjugateUnconjugated
- Gene ID51191
- Target nameHERC5
- Target descriptionHECT and RLD domain containing E3 ubiquitin protein ligase 5
- Target synonymsCEB1; CEBP1; cyclin-E-binding protein 1; E3 ISG15--protein ligase HERC5; HECT domain and RCC1-like domain-containing protein 5; hect domain and RLD 5; probable E3 ubiquitin-protein ligase HERC5
- HostRabbit
- IsotypeIgG
- Protein IDQ9UII4
- Protein NameE3 ISG15--protein ligase HERC5
- Scientific DescriptionThis gene is a member of the HERC family of ubiquitin ligases and encodes a protein with a HECT domain and five RCC1 repeats. Pro-inflammatory cytokines upregulate expression of this gene in endothelial cells. The protein localizes to the cytoplasm and perinuclear region and functions as an interferon-induced E3 protein ligase that mediates ISGylation of protein targets. The gene lies in a cluster of HERC family genes on chromosome 4. [provided by RefSeq]
- ReactivityHuman
- Storage Instruction-20°C or -80°C,2°C to 8°C
- UNSPSC12352203
References
- Induced TRIM21 ISGylation by IFN-beta enhances p62 ubiquitination to prevent its autophagosome targeting. Jin J et al., 2021 Jul 13, Cell Death DisRead more