Bio-Connect

HERC5 antibody

GTX130167
GeneTex
ApplicationsWestern Blot
Product group Antibodies
ReactivityHuman
TargetHERC5
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Overview

  • Supplier
    GeneTex
  • Product Name
    HERC5 antibody
  • Delivery Days Customer
    9
  • Application Supplier Note
    WB: 1:500-1:3000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
  • Applications
    Western Blot
  • Certification
    Research Use Only
  • Clonality
    Polyclonal
  • Concentration
    3.96 mg/ml
  • Conjugate
    Unconjugated
  • Gene ID51191
  • Target name
    HERC5
  • Target description
    HECT and RLD domain containing E3 ubiquitin protein ligase 5
  • Target synonyms
    CEB1; CEBP1; cyclin-E-binding protein 1; E3 ISG15--protein ligase HERC5; HECT domain and RCC1-like domain-containing protein 5; hect domain and RLD 5; probable E3 ubiquitin-protein ligase HERC5
  • Host
    Rabbit
  • Isotype
    IgG
  • Protein IDQ9UII4
  • Protein Name
    E3 ISG15--protein ligase HERC5
  • Scientific Description
    This gene is a member of the HERC family of ubiquitin ligases and encodes a protein with a HECT domain and five RCC1 repeats. Pro-inflammatory cytokines upregulate expression of this gene in endothelial cells. The protein localizes to the cytoplasm and perinuclear region and functions as an interferon-induced E3 protein ligase that mediates ISGylation of protein targets. The gene lies in a cluster of HERC family genes on chromosome 4. [provided by RefSeq]
  • Reactivity
    Human
  • Storage Instruction
    -20°C or -80°C,2°C to 8°C
  • UNSPSC
    12352203

References

  • Induced TRIM21 ISGylation by IFN-beta enhances p62 ubiquitination to prevent its autophagosome targeting. Jin J et al., 2021 Jul 13, Cell Death Dis
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