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ProductsBack/Heronamide C

Heronamide C

ORB2299217

CAS Number1257083-94-5

Product group Chemicals

Estimated Purity98.00%

Molecular Weight449.635

Overview

Supplier
Biorbyt
Product Name
Heronamide C
Delivery Days Customer
10
CAS Number
1257083-94-5
Certification
Research Use Only
Estimated Purity
98.00%
Molecular Formula
C29H39NO3
Molecular Weight
449.635
Scientific Description
Heronamide C, a polyketide macrolactam antifungal agent synthesized by marine Actinomycetes, exhibits selective toxicity by inhibiting growth and promoting abnormal cell wall material accumulation in wild-type fission yeast cells (MIC = 0.13-0.28 microM), without affecting Gram-positive bacteria or human cancer cell lines, HeLa and MDA-MB-231. At 20 microM, it triggers reversible morphological alterations, notably the development of large intracellular structures, in HeLa cells.
SMILES
[H][C@@]1(C\C=C\C=C\CCC)C\C=C\C=C(/C)\C=C\C=C/[C@H](O)[C@H](O)\C=C(/C)\C=C\C=C\C(=O)N1
Storage Instruction
-20°C
UNSPSC
12352200

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