HET0016

MedChem Express

HET0016 [339068-25-6]

10

339068-25-6

Research Use Only

99.69

C12H18N2O

206.28

HET0016 is a potent and selective 20-hydroxyeicosatetraenoic acid (20-HETE) synthase inhibitor, with IC 50 values of 17.7 nM, 12.1 nM and 20.6 nM for recombinant CYP4A1-, CYP4A2- and CYP4A3-catalyzed 20-HETE synthesis, respectively. HET0016 also is a selective CYP450 inhibitor, which has been shown to inhibit angiogenesis and tumor growth [1] [2] .

CCCCC1=CC=C(C(C)=C1)/N=C/NO

-20°C,2°C to 8°C

12352200