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WB analysis of K562 cell lysates using GTX87082 HEY2 antibody. The lane on the right is blocked with the synthesized peptide.
WB analysis of K562 cell lysates using GTX87082 HEY2 antibody. The lane on the right is blocked with the synthesized peptide.
WB analysis of K562 cell lysates using GTX87082 HEY2 antibody. The lane on the right is blocked with the synthesized peptide.

HEY2 antibody

GTX87082
GeneTex
ApplicationsWestern Blot
Product group Antibodies
ReactivityHuman
TargetHEY2
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Overview

  • Supplier
    GeneTex
  • Product Name
    HEY2 antibody
  • Delivery Days Customer
    9
  • Application Supplier Note
    WB: 1:500~1:1000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
  • Applications
    Western Blot
  • Certification
    Research Use Only
  • Clonality
    Polyclonal
  • Conjugate
    Unconjugated
  • Gene ID23493
  • Target name
    HEY2
  • Target description
    hes related family bHLH transcription factor with YRPW motif 2
  • Target synonyms
    bHLHb32; cardiovascular basic helix-loop-helix factor 1; cardiovascular helix-loop-helix factor 1; CHF1; class B basic helix-loop-helix protein 32; GRIDLOCK; GRL; hairy and enhancer of split-related protein 2; hairy/enhancer-of-split related with YRPW motif 2; hairy/enhancer-of-split related with YRPW motif protein 2; hairy-related transcription factor 2; hCHF1; HERP1; HESR2; HESR-2; HES-related repressor protein 1; HES-related repressor protein 2; hHRT2; HRT2; HRT-2; protein gridlock homolog
  • Host
    Rabbit
  • Isotype
    IgG
  • Protein IDQ9UBP5
  • Protein Name
    Hairy/enhancer-of-split related with YRPW motif protein 2
  • Scientific Description
    This gene encodes a member of the hairy and enhancer of split-related (HESR) family of basic helix-loop-helix (bHLH)-type transcription factors. The encoded protein forms homo- or hetero-dimers that localize to the nucleus and interact with a histone deacetylase complex to repress transcription. Expression of this gene is induced by the Notch signal transduction pathway. Two similar and redundant genes in mouse are required for embryonic cardiovascular development, and are also implicated in neurogenesis and somitogenesis. Alternatively spliced transcript variants have been found, but their biological validity has not been determined. [provided by RefSeq, Jul 2008]
  • Reactivity
    Human
  • Storage Instruction
    -20°C or -80°C,2°C to 8°C
  • UNSPSC
    12352203

References

  • HEY2 acting as a co-repressor with smad3 and smad4 interferes with the response of TGF-beta in hepatocellular carcinoma. Wang J et al., 2019, Am J Transl Res
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