HGFR, Cynomolgus/Rhesus Macaque (HEK293, His)
HY-P72937
Product group Proteins / Signaling Molecules
Overview
- SupplierMedChem Express
- Product NameHGFR, Cynomolgus/Rhesus Macaque (HEK293, His)
- Delivery Days Customer10
- CertificationResearch Use Only
- Gene ID704562
- Target nameMET
- Target descriptionMET proto-oncogene, receptor tyrosine kinase
- Target synonymsEGK_14061, hepatocyte growth factor receptor, met proto-oncogene (hepatocyte growth factor receptor)
- Scientific DescriptionHGFR Protein, a receptor tyrosine kinase, transduces signals by binding hepatocyte growth factor/HGF ligand. It regulates proliferation, scattering, morphogenesis, and cell survival. Upon ligand binding, HGFR undergoes autophosphorylation, creating docking sites for downstream molecules like PI3K, PLCG1, SRC, GRB2, STAT3, or GAB1, activating RAS-ERK, PI3K-AKT, and PLCgamma-PKC cascades. HGFR Protein, Cynomolgus/Rhesus Macaque (HEK293, His) is the recombinant Rhesus Macaque, cynomolgus-derived HGFR protein, expressed by HEK293 , with C-His labeled tag.
- UNSPSC41116100
- SpeciesPrimate