HGFR, Mouse (HEK293, His)
HY-P72941
Product group Proteins / Signaling Molecules
Overview
- SupplierMedChem Express
- Product NameHGFR, Mouse (HEK293, His)
- Delivery Days Customer10
- CertificationResearch Use Only
- Estimated Purity95.00
- Gene ID17295
- Target nameMet
- Target descriptionmet proto-oncogene
- Target synonymsAI838057; c-Met; hepatocyte growth factor receptor; HGF; HGF receptor; HGF/SF receptor; HGFR; met proto-oncogene tyrosine kinase; P; Par4; proto-oncogene c-Met; scatter factor receptor; SF receptor; tyrosine-protein kinase Met
- Scientific DescriptionHGFR Protein, a receptor tyrosine kinase, transduces signals by binding hepatocyte growth factor/HGF ligand. It regulates proliferation, scattering, morphogenesis, and cell survival. Upon ligand binding, HGFR undergoes autophosphorylation, creating docking sites for downstream molecules like PI3K, PLCG1, SRC, GRB2, STAT3, or GAB1, activating RAS-ERK, PI3K-AKT, and PLCgamma-PKC cascades. HGFR Protein, Mouse (HEK293, His) is the recombinant mouse-derived HGFR protein, expressed by HEK293 , with C-His labeled tag.
- Storage Instruction-20°C
- UNSPSC41116100