ProductsBack/Hice1 (phospho Ser 19/20) antibody

Hice1 (phospho Ser 19/20) antibody

Name: Hice1 (phospho Ser 19/20) antibody
SKU: GTX70011_G10
Price: 511 EUR
Availability: BackOrder

GTX70011

ApplicationsImmunoFluorescence, Western Blot, ELISA, ImmunoCytoChemistry

Product group Antibodies

ReactivityHuman

TargetHAUS8

Overview

Supplier
GeneTex
Product Name
Hice1 (phospho Ser 19/20) antibody
Delivery Days Customer
9
Applications
ImmunoFluorescence, Western Blot, ELISA, ImmunoCytoChemistry
Certification
Research Use Only
Clonality
Polyclonal
Conjugate
Unconjugated
Gene ID93323
Target name
HAUS8
Target description
HAUS augmin like complex subunit 8
Target synonyms
DGT4; HAUS augmin-like complex subunit 8; HEC1/NDC80 interacting, centrosome associated 1; HEC1/NDC80-interacting centrosome-associated protein 1; Hec1-interacting and centrosome-associated 1; HICE1; NY-SAR-48; sarcoma antigen NY-SAR-48
Host
Rabbit
Isotype
IgG
Modification Type
Phosphorylated
Scientific Description
HAUS8 is 1 of 8 subunits of the 390-kD human augmin complex, or HAUS complex. The augmin complex was first identified in Drosophila, and its name comes from the Latin verb augmentare, meaning to increase. The augmin complex is a microtubule-binding complex involved in microtubule generation within the mitotic spindle and is vital to mitotic spindle assembly (Goshima et al., 2008 [PubMed 18443220]; Uehara et al., 2009 [PubMed 19369198]).[supplied by OMIM, Jun 2010]
Reactivity
Human
Storage Instruction
2°C to 8°C,-20°C or -80°C
UNSPSC
12352203

Aurora-A phosphorylates Augmin complex component Hice1 protein at an N-terminal serine/threonine cluster to modulate its microtubule binding activity during spindle assembly. Tsai CY et al., 2011 Aug 26, J Biol Chem
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