Hice1 (phospho Ser19/Ser20) antibody
GTX70011
ApplicationsImmunoFluorescence, Western Blot, ELISA, ImmunoCytoChemistry
Product group Antibodies
ReactivityHuman
TargetHAUS8
Overview
- SupplierGeneTex
- Product NameHice1 (phospho Ser 19/20) antibody
- Delivery Days Customer9
- Application Supplier NoteRecommended Starting Dilutions:For WB: Use at a dilution of 1:100For ICC/IF: Use at a dilution of 1:50Not yet tested in other applications. Optimal dilutions should be determined experimentally by the researcher.
- ApplicationsImmunoFluorescence, Western Blot, ELISA, ImmunoCytoChemistry
- CertificationResearch Use Only
- ClonalityPolyclonal
- ConjugateUnconjugated
- Gene ID93323
- Target nameHAUS8
- Target descriptionHAUS augmin like complex subunit 8
- Target synonymsDGT4; HAUS augmin-like complex subunit 8; HEC1/NDC80 interacting, centrosome associated 1; HEC1/NDC80-interacting centrosome-associated protein 1; Hec1-interacting and centrosome-associated 1; HICE1; NY-SAR-48; sarcoma antigen NY-SAR-48
- HostRabbit
- IsotypeIgG
- Protein IDQ9BT25
- Protein NameHAUS augmin-like complex subunit 8
- Scientific DescriptionHAUS8 is 1 of 8 subunits of the 390-kD human augmin complex, or HAUS complex. The augmin complex was first identified in Drosophila, and its name comes from the Latin verb augmentare, meaning to increase. The augmin complex is a microtubule-binding complex involved in microtubule generation within the mitotic spindle and is vital to mitotic spindle assembly (Goshima et al., 2008 [PubMed 18443220]; Uehara et al., 2009 [PubMed 19369198]).[supplied by OMIM, Jun 2010]
- ReactivityHuman
- Storage Instruction-20°C or -80°C,2°C to 8°C
- UNSPSC12352203
References
- Aurora-A phosphorylates Augmin complex component Hice1 protein at an N-terminal serine/threonine cluster to modulate its microtubule binding activity during spindle assembly. Tsai CY et al., 2011 Aug 26, J Biol ChemRead more