HIF1 beta antibody [4C5]

GeneTex

HIF1 beta antibody [4C5]

9

WB: 1:1000-1:2000. IHC-P: 1:100-1:200. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.

Western Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin

Research Use Only

Monoclonal

4C5

1 mg/ml

Unconjugated

ARNT

aryl hydrocarbon receptor nuclear translocator

aryl hydrocarbon receptor nuclear translocator; bHLHe2; class E basic helix-loop-helix protein 2; dioxin receptor, nuclear translocator; HIF1B; HIF1BETA; HIF-1beta; HIF-1-beta; HIF1-beta; hypoxia-inducible factor 1, beta subunit; TANGO

Mouse

IgG1

Aryl hydrocarbon receptor nuclear translocator

This gene encodes a protein containing a basic helix-loop-helix domain and two characteristic PAS domains along with a PAC domain. The encoded protein binds to ligand-bound aryl hydrocarbon receptor and aids in the movement of this complex to the nucleus, where it promotes the expression of genes involved in xenobiotic metabolism. This protein is also a co-factor for transcriptional regulation by hypoxia-inducible factor 1. Chromosomal translocation of this locus with the ETV6 (ets variant 6) gene on chromosome 12 have been described in leukemias. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2013]

Mouse

-20°C or -80°C,2°C to 8°C

12352203