IHC-P analysis of hmuan colon tissue section using GTX00799 HIF1 beta antibody [GT1141]. Dlution : 1:100
HIF1 beta antibody [GT1141]
GTX00799
ApplicationsWestern Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
Product group Antibodies
ReactivityHuman
TargetARNT
Overview
- SupplierGeneTex
- Product NameHIF1 beta antibody [GT1141]
- Delivery Days Customer9
- ApplicationsWestern Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
- CertificationResearch Use Only
- ClonalityMonoclonal
- Clone IDGT1141
- ConjugateUnconjugated
- Gene ID405
- Target nameARNT
- Target descriptionaryl hydrocarbon receptor nuclear translocator
- Target synonymsaryl hydrocarbon receptor nuclear translocator; bHLHe2; class E basic helix-loop-helix protein 2; dioxin receptor, nuclear translocator; HIF1B; HIF1BETA; HIF-1beta; HIF-1-beta; HIF1-beta; hypoxia-inducible factor 1, beta subunit; TANGO
- HostRabbit
- IsotypeIgG
- Scientific DescriptionThis gene encodes a protein containing a basic helix-loop-helix domain and two characteristic PAS domains along with a PAC domain. The encoded protein binds to ligand-bound aryl hydrocarbon receptor and aids in the movement of this complex to the nucleus, where it promotes the expression of genes involved in xenobiotic metabolism. This protein is also a co-factor for transcriptional regulation by hypoxia-inducible factor 1. Chromosomal translocation of this locus with the ETV6 (ets variant 6) gene on chromosome 12 have been described in leukemias. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2013]
- ReactivityHuman
- Storage Instruction2°C to 8°C,-20°C or -80°C
- UNSPSC12352203