Higenamine-d4-1 (hydrochloride)

MedChem Express

Higenamine-d4-1 (hydrochloride)

5

Research Use Only

C16H14D4ClNO3

311.80

Higenamine-d4-1 (Norcoclaurine-d4-1) hydrochloride is deuterium labeled Higenamine (hydrochloride). Higenamine hydrochloride is a selective LSD1 inhibitor (IC50=1.47 microM) that can be isolated from aconite. Higenamine hydrochloride has anti-inflammatory and antibacterial activity. Higenamine (Norcoclaurine) can attenuate IL-1beta-induced Apoptosis through ROS-mediated PI3K/Akt signaling pathway. Higenamine hydrochloride protects brain cells from oxygen deprivation. Higenamine can promote bone formation in osteoporosis through the SMAD2/3 pathway. Higenamine hydrochloride can be used to study cancer, inflammation, cardiorenal syndrome and other diseases[1][2][3][4][5][6][7].

[2H]C(C([2H])=C(O)C([2H])=C1[2H])=C1CC2NCCC3=C2C=C(O)C(O)=C3.Cl

12352200