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Higenamine (hydrochloride)

HY-N2037A
MedChem Express
CAS Number11041-94-4
DownloadMSDS
Product group Chemicals
Estimated Purity99.68
Molecular Weight307.77
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Overview

  • Supplier
    MedChem Express
  • Product Name
    Higenamine (hydrochloride) [11041-94-4]
  • Delivery Days Customer
    5
  • CAS Number
    11041-94-4
  • Certification
    Research Use Only
  • Estimated Purity
    99.68
  • Molecular Formula
    C16H18ClNO3
  • Molecular Weight
    307.77
  • Scientific Description
    Higenamine hydrochloride is a selective LSD1 inhibitor ( IC 50 =1.47 microM) that can be isolated from aconite. Higenamine hydrochloride has anti-inflammatory and antibacterial activity. Higenamine (Norcoclaurine) can attenuate IL-1beta-induced Apoptosis through ROS-mediated PI3K/Akt signaling pathway. Higenamine hydrochloride protects brain cells from oxygen deprivation. Higenamine can promote bone formation in osteoporosis through the SMAD2/3 pathway. Higenamine hydrochloride can be used to study cancer, inflammation, cardiorenal syndrome and other diseases [1] [2] [3] [4] [5] [6] .
  • SMILES
    OC1=CC2=C(C(CC3=CC=C(O)C=C3)NCC2)C=C1O.[H]Cl
  • Storage Instruction
    2°C to 8°C
  • UNSPSC
    12352200