Higenamine (hydrochloride)

MedChem Express

Higenamine (hydrochloride) [11041-94-4]

5

11041-94-4

Research Use Only

99.68

C16H18ClNO3

307.77

Higenamine hydrochloride is a selective LSD1 inhibitor ( IC 50 =1.47 microM) that can be isolated from aconite. Higenamine hydrochloride has anti-inflammatory and antibacterial activity. Higenamine (Norcoclaurine) can attenuate IL-1beta-induced Apoptosis through ROS-mediated PI3K/Akt signaling pathway. Higenamine hydrochloride protects brain cells from oxygen deprivation. Higenamine can promote bone formation in osteoporosis through the SMAD2/3 pathway. Higenamine hydrochloride can be used to study cancer, inflammation, cardiorenal syndrome and other diseases [1] [2] [3] [4] [5] [6] .

OC1=CC2=C(C(CC3=CC=C(O)C=C3)NCC2)C=C1O.[H]Cl

2°C to 8°C

12352200