
Immunohistochemistry of paraffin-embedded human bladder cancer using CSB-PA872492LA01HU at dilution of 1:100
HIPK3 Antibody
CSB-PA872492LA01HU
ApplicationsImmunoFluorescence, ELISA, ImmunoHistoChemistry
Product group Antibodies
TargetHIPK3
Overview
- SupplierCusabio
- Product NameHIPK3 Antibody
- Delivery Days Customer20
- ApplicationsImmunoFluorescence, ELISA, ImmunoHistoChemistry
- CertificationResearch Use Only
- ClonalityPolyclonal
- ConjugateUnconjugated
- Gene ID10114
- Target nameHIPK3
- Target descriptionhomeodomain interacting protein kinase 3
- Target synonymsandrogen receptor-interacting nuclear protein kinase; ANPK; DYRK6; fas-interacting serine/threonine-protein kinase; FIST; FIST3; homeodomain-interacting protein kinase 3; homolog of protein kinase YAK1; PKY; YAK1
- HostRabbit
- IsotypeIgG
- Protein IDQ9H422
- Protein NameHomeodomain-interacting protein kinase 3
- Scientific DescriptionSerine/threonine-protein kinase involved in transcription regulation, apoptosis and steroidogenic gene expression. Phosphorylates JUN and RUNX2. Seems to negatively regulate apoptosis by promoting FADD phosphorylation. Enhances androgen receptor-mediated transcription. May act as a transcriptional corepressor for NK homeodomain transcription factors. The phosphorylation of NR5A1 activates SF1 leading to increased steroidogenic gene expression upon cAMP signaling pathway stimulation. In osteoblasts, supports transcription activation: phosphorylates RUNX2 that synergizes with SPEN/MINT to enhance FGFR2-mediated activation of the osteocalcin FGF-responsive element (OCFRE).
- Storage Instruction-20°C or -80°C
- UNSPSC12352203