Histamine H2 Receptor antibody [N1], N-term
GTX108152
ApplicationsFlow Cytometry, ImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
Product group Antibodies
ReactivityHuman, Rat
TargetHRH2
Overview
- SupplierGeneTex
- Product NameHistamine H2 Receptor antibody [N1], N-term
- Delivery Days Customer9
- Application Supplier NoteWB: 1:500-1:3000. IHC-P: 1:100-1:1000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
- ApplicationsFlow Cytometry, ImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
- CertificationResearch Use Only
- ClonalityPolyclonal
- Concentration0.75 mg/ml
- ConjugateUnconjugated
- Gene ID3274
- Target nameHRH2
- Target descriptionhistamine receptor H2
- Target synonymsgastric receptor 1; gastric receptor I; H2R; HH2R; histamine H2 receptor
- HostRabbit
- IsotypeIgG
- Protein IDP25021
- Protein NameHistamine H2 receptor
- Scientific DescriptionHistamine is a ubiquitous messenger molecule released from mast cells, enterochromaffin-like cells, and neurons. Its various actions are mediated by histamine receptors H1, H2, H3 and H4. Histamine receptor H2 belongs to the family 1 of G protein-coupled receptors. It is an integral membrane protein and stimulates gastric acid secretion. It also regulates gastrointestinal motility and intestinal secretion and is thought to be involved in regulating cell growth and differentiation. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq]
- ReactivityHuman, Rat
- Storage Instruction-20°C or -80°C,2°C to 8°C
- UNSPSC12352203
References
- A human liver cell-based system modeling a clinical prognostic liver signature for therapeutic discovery. Crouchet E et al., 2021 Sep 17, Nat CommunRead more
- Suppression of osteogenic differentiation in mesenchymal stem cells from patients with ossification of the posterior longitudinal ligament by a histamine-2-receptor antagonist. Liu X et al., 2017 Sep 5, Eur J PharmacolRead more
- Involvement of the H1 Histamine Receptor, p38 MAP Kinase, Myosin Light Chains Kinase, and Rho/ROCK in Histamine-Induced Endothelial Barrier Dysfunction. Adderley SP et al., 2015 May, MicrocirculationRead more
- Involvement of H1 and H2 receptors and soluble guanylate cyclase in histamine-induced relaxation of rat mesenteric collecting lymphatics. Kurtz KH et al., 2014 Oct, MicrocirculationRead more
- Histamine receptor 2 modifies dendritic cell responses to microbial ligands. Frei R et al., 2013 Jul, J Allergy Clin ImmunolRead more