Bio-Connect

Histamine H2 Receptor antibody [N1], N-term

GTX108152
GeneTex
ApplicationsFlow Cytometry, ImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
Product group Antibodies
ReactivityHuman, Rat
TargetHRH2
Sign in to order and to see your custom pricing.
Large volume orders?
Order with a bulk request

Overview

  • Supplier
    GeneTex
  • Product Name
    Histamine H2 Receptor antibody [N1], N-term
  • Delivery Days Customer
    9
  • Application Supplier Note
    WB: 1:500-1:3000. IHC-P: 1:100-1:1000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
  • Applications
    Flow Cytometry, ImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
  • Certification
    Research Use Only
  • Clonality
    Polyclonal
  • Concentration
    0.75 mg/ml
  • Conjugate
    Unconjugated
  • Gene ID3274
  • Target name
    HRH2
  • Target description
    histamine receptor H2
  • Target synonyms
    gastric receptor 1; gastric receptor I; H2R; HH2R; histamine H2 receptor
  • Host
    Rabbit
  • Isotype
    IgG
  • Protein IDP25021
  • Protein Name
    Histamine H2 receptor
  • Scientific Description
    Histamine is a ubiquitous messenger molecule released from mast cells, enterochromaffin-like cells, and neurons. Its various actions are mediated by histamine receptors H1, H2, H3 and H4. Histamine receptor H2 belongs to the family 1 of G protein-coupled receptors. It is an integral membrane protein and stimulates gastric acid secretion. It also regulates gastrointestinal motility and intestinal secretion and is thought to be involved in regulating cell growth and differentiation. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq]
  • Reactivity
    Human, Rat
  • Storage Instruction
    -20°C or -80°C,2°C to 8°C
  • UNSPSC
    12352203

References

  • A human liver cell-based system modeling a clinical prognostic liver signature for therapeutic discovery. Crouchet E et al., 2021 Sep 17, Nat Commun
    Read more
  • Suppression of osteogenic differentiation in mesenchymal stem cells from patients with ossification of the posterior longitudinal ligament by a histamine-2-receptor antagonist. Liu X et al., 2017 Sep 5, Eur J Pharmacol
    Read more
  • Involvement of the H1 Histamine Receptor, p38 MAP Kinase, Myosin Light Chains Kinase, and Rho/ROCK in Histamine-Induced Endothelial Barrier Dysfunction. Adderley SP et al., 2015 May, Microcirculation
    Read more
  • Involvement of H1 and H2 receptors and soluble guanylate cyclase in histamine-induced relaxation of rat mesenteric collecting lymphatics. Kurtz KH et al., 2014 Oct, Microcirculation
    Read more
  • Histamine receptor 2 modifies dendritic cell responses to microbial ligands. Frei R et al., 2013 Jul, J Allergy Clin Immunol
    Read more