Histatin-3 [112844-49-2]
T78224
Overview
- SupplierTargetMol Chemicals
- Product NameHistatin-3 [112844-49-2]
- Delivery Days Customer999
- Category SupplierChemical
- CertificationResearch Use Only
- Chemical NameHistatin-3
- Molecular FormulaC178H258N64O48
- Molecular Weight4062.35
- Scientific DescriptionHistatin-3, a 32-amino-acid peptide, exhibits potent antimicrobial activities and serves as a substrate for proprotein convertase 1 (PC1), where it is primarily cleaved at a site carboxy-terminal to Arg25 (HRGYRSN). Additionally, it acts as a moderately potent, reversible, and competitive inhibitor of furin-mediated cleavage of the pentapeptide pGlu-Arg-Thr-Lys-Arg-MCA fluorogenic substrate, with an inhibition constant (Ki) estimated at 1.98 microM [1].
- Shelf life instruction3 years
- Storage Instruction-20°C
- UNSPSC12352200