Bio-Connect

Histatin-3 [112844-49-2]

T78224
TargetMol Chemicals
Molecular Weight4062.35
Product group Chemicals
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Overview

  • Supplier
    TargetMol Chemicals
  • Product Name
    Histatin-3 [112844-49-2]
  • Delivery Days Customer
    999
  • Category Supplier
    Chemical
  • Certification
    Research Use Only
  • Chemical Name
    Histatin-3
  • Molecular Formula
    C178H258N64O48
  • Molecular Weight
    4062.35
  • Scientific Description
    Histatin-3, a 32-amino-acid peptide, exhibits potent antimicrobial activities and serves as a substrate for proprotein convertase 1 (PC1), where it is primarily cleaved at a site carboxy-terminal to Arg25 (HRGYRSN). Additionally, it acts as a moderately potent, reversible, and competitive inhibitor of furin-mediated cleavage of the pentapeptide pGlu-Arg-Thr-Lys-Arg-MCA fluorogenic substrate, with an inhibition constant (Ki) estimated at 1.98 microM [1].
  • Shelf life instruction
    3 years
  • Storage Instruction
    -20°C
  • UNSPSC
    12352200