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Histone H3K27me3 (Tri-methyl Lys27) antibody

GTX121184
GeneTex
ApplicationsDot Blot, Electron Microscopy, ImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Frozen, ImmunoHistoChemistry Paraffin
Product group Antibodies
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Overview

  • Supplier
    GeneTex
  • Product Name
    Histone H3K27me3 (Tri-methyl Lys27) antibody
  • Delivery Days Customer
    9
  • Application Supplier Note
    WB: 1:500-1:3000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. IHC-Fr: 1:100-1:1000. IHC-Wm: 1:100-1:500. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
  • Applications
    Dot Blot, Electron Microscopy, ImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Frozen, ImmunoHistoChemistry Paraffin
  • Certification
    Research Use Only
  • Clonality
    Polyclonal
  • Concentration
    1 mg/ml
  • Conjugate
    Unconjugated
  • Host
    Rabbit
  • Isotype
    IgG
  • Storage Instruction
    -20°C or -80°C,2°C to 8°C
  • UNSPSC
    12352203

References

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  • Perrigue PM, Rakoczy M, Pawlicka KP, et al. Cancer Stem Cell-Inducing Media Activates Senescence Reprogramming in Fibroblasts. Cancers (Basel). 2020,12(7). doi: 10.3390/cancers12071745
    Read this paper
  • Zhang T, Du E, Liu Y, et al. Anticancer Effects of Zinc Oxide Nanoparticles Through Altering the Methylation Status of Histone on Bladder Cancer Cells. Int J Nanomedicine. 2020,15:1457-1468. doi: 10.2147/IJN.S228839
    Read this paper
  • Hasebe T, Fujimoto K, Buchholz DR, et al. Stem cell development involves divergent thyroid hormone receptor subtype expression and epigenetic modifications in the Xenopus metamorphosing intestine. Gen Comp Endocrinol. 2020,292:113441. doi: 10.1016/j.ygcen.2020.113441
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  • Tanrıkulu B, Danyeli AE, Özek MM. Is H3K27me3 status really a strong prognostic indicator for pediatric posterior fossa ependymomas? A single surgeon, single center experience. Childs Nerv Syst. 2020,36(5):941-949. doi: 10.1007/s00381-020-04518-5
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  • Blin G, Liand M, Mauduit C, et al. Maternal Exposure to High-Fat Diet Induces Long-Term Derepressive Chromatin Marks in the Heart. Nutrients. 2020,12(1). doi: 10.3390/nu12010181
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  • Tsuyama N, Asaka R, Dobashi A, et al. Epstein-Barr virus-negative extranodal "true" natural killer-cell lymphoma harbouring a KDM6A mutation. Hematol Oncol. 2018,36(1):328-335. doi: 10.1002/hon.2459
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  • Mirzamohammadi F, Papaioannou G, Inloes JB, et al. Polycomb repressive complex 2 regulates skeletal growth by suppressing Wnt and TGF-β signalling. Nat Commun. 2016,7:12047. doi: 10.1038/ncomms12047
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  • Perrigue PM, Silva ME, Warden CD, et al. The histone demethylase jumonji coordinates cellular senescence including secretion of neural stem cell-attracting cytokines. Mol Cancer Res. 2015,13(4):636-50. doi: 10.1158/1541-7786.MCR-13-0268
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  • Liu TP, Lo HL, Wei LS, et al. S-Adenosyl-L-methionine-competitive inhibitors of the histone methyltransferase EZH2 induce autophagy and enhance drug sensitivity in cancer cells. Anticancer Drugs. 2015,26(2):139-47. doi: 10.1097/CAD.0000000000000166
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