Hit 14 [440338-68-1]

TargetMol Chemicals

Hit 14 [440338-68-1]

9

Research Use Only

C22H28N2O7S2

496.6

Hit 14, a CXCR4 (C-X-C chemokine receptor type 4) inhibitor, demonstrates an IC50 of 254 nM. It inhibits migration and invasion of MDA-MB-231 cells and suppresses Akt phosphorylation, exhibiting anti-inflammatory activity. Furthermore, Hit 14 improves ear swelling and damage in a mouse model.

O=S(=O)(NCC1OCCC1)C2=CC=C(OC3=CC=C(C=C3)S(=O)(=O)NCC4OCCC4)C=C2

-20°C

12352200