HIV-1 inhibitor-21 [2554620-04-9]
HY-146015
CAS Number2554620-04-9
Product group Chemicals
Molecular Weight476.53
Overview
- SupplierMedChem Express
- Product NameHIV-1 inhibitor-21 [2554620-04-9]
- Delivery Days Customer10
- CAS Number2554620-04-9
- CertificationResearch Use Only
- Molecular FormulaC28H24N6O2
- Molecular Weight476.53
- Scientific DescriptionHIV-1 inhibitor-21 (compound 9b) is a potent HIV-1 non-nucleoside reverse transcriptase (RT) inhibitor, with an IC50 value of 0.55 microM for HIV-1 RT. HIV-1 inhibitor-21 has antiretroviral activity against HIV-1 WT and K103N strains with EC50s of 12.7 nM and 10.4 nM, and has relatively low cytotoxicity (MT-4 cells CC50 =10.2 microM)[1].
- SMILESN#CC1=CC=C(NC2=NC(NC3=C(C)C=C(/C=C/C#N)C=C3C)=C4C=C(OC)C(OC)=CC4=N2)C=C1
- UNSPSC12131703