HIV-1 inhibitor-28 [2642218-07-1]

MedChem Express

HIV-1 inhibitor-28 [2642218-07-1]

10

2642218-07-1

Research Use Only

C26H32N6O3S

508.64

HIV-1 inhibitor-28 (compound 14j2) is a highly potent and selective HIV-1 inhibitor with an EC50 of 58 nM for WT HIV-1 strain and an IC50 of 3.37 microM for HIV-1 WT reverse transcription (RT). HIV-1 inhibitor-28 exhibits relatively low cytotoxicity in MT-4 cells (CC50 = 38.6 microM). HIV-1 inhibitor-28 can be used for researching AIDS[1].

CC1=CC(C#N)=CC(C)=C1OC2=C3SCCC3=NC(NC4CCN(CC4)CC(N5CCOCC5)=O)=N2

12131703