HIV-1 inhibitor-29 [2642217-95-4]

MedChem Express

HIV-1 inhibitor-29 [2642217-95-4]

10

2642217-95-4

Research Use Only

C30H36N6O5

560.64

HIV-1 inhibitor-29 (compound 14d2) is a potent HIV-1 inhibitor with an EC50 of 2.18 microM for HIV-1 IIIB. HIV-1 inhibitor-29 has high anti-resistance profile toward F227L/V106A strain (EC50 = 0.974 microM), and exhibits low cytotoxicity in MT-4 cells (CC50 = 211 microM). HIV-1 inhibitor-29 can be used for researching AIDS[1].

COC1=CC2=NC(NC3CCN(CC3)CC(N4CCOCC4)=O)=NC(OC5=C(C=C(C=C5C)C#N)C)=C2C=C1OC

12131703