HIV-1 p17/p24/gp120/gp41, Human Immunodeficiency Virus 1 Antigens, recombinant, E. coli

Jena Bioscience

HIV-1 p17/p24/gp120/gp41, Human Immunodeficiency Virus 1 Antigens, recombinant, E. coli

5

Western Blot, ELISA

Research Use Only

>95%

The protein contains the full-length sequence of HIV-1 core and envelope proteins: Core protein p17 (Matrix protein), Core protein p24 (Core antigen) fused with membrane glycoprotein (gp120) and transmembrane glycoprotein (gp41). The fusion protein was purified by proprietary chromatographic technique. Background: HIV belongs to the retrovirus family, distinguished by possession of a viral reverse transcriptase that transcribes viral RNA into DNA which is integrated into the host-cell genome. The outer envelope is acquired during virion budding and is studded with spikes formed by the two major viral-envelope glycoproteins (the surface protein gp120 and the transmembrane protein gp41). The central core contains four viral proteins (p24 - the major capsid protein, p17 - a matrix protein, p9, and p7), two copies of the HIV RNA genome (to which p7 and p9 are bound), and three viral enzymes (reverse transcriptase, integrase, and protease) essential for viral replication.

-20°C

12352202