HJC0197 [1383539-73-8]

MedChem Express

HJC0197 [1383539-73-8]

5

1383539-73-8

Research Use Only

99.62

C19H21N3OS

339.45

HJC0197 is a potent Epac1 (exchange protein directly activated by cAMP 1) and Epac2 (IC50=5.9 microM for Epac2) antagonist. HJC0197 selectively blocks cAMP-induced Epac activation. HJC0197 inhibits Epac1-mediated Rap1-GDP exchange activity at 25 microM in the presence of equal concentration of cAMP[1].

N#CC1=C(C2CCCC2)N=C(SCC3=CC(C)=CC=C3C)NC1=O

-20°C,2°C to 8°C

12352200