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HKI-357 dimaleate [915942-25-5]

HKI-357 dimaleate [915942-25-5]

T68360
TargetMol Chemicals
Molecular Weight806.2
Product group Chemicals
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Overview

  • Supplier
    TargetMol Chemicals
  • Product Name
    HKI-357 dimaleate [915942-25-5]
  • Delivery Days Customer
    72
  • Certification
    Research Use Only
  • Chemical Name
    HKI-357 dimaleate
  • Molecular Formula
    C39H37ClFN5O11
  • Molecular Weight
    806.2
  • Scientific Description
    HKI-357 dimaleate is an irreversible dual inhibitor of EGFR and ERBB2. HKI-357 suppresses EGFR autophosphorylation (at Y1068), and AKT and MAPK phosphorylation.
  • Shelf life instruction
    3 years
  • SMILES
    OC(=O)\C=C/C(O)=O.OC(=O)\C=C/C(O)=O.CCOc1cc2ncc(C#N)c(Nc3ccc(OCc4cccc(F)c4)c(Cl)c3)c2cc1NC(=O)\C=C\CN(C)C
  • Storage Instruction
    -20°C
  • UNSPSC
    12352200