HLA Class I antibody [W6/32]

GeneTex

HLA Class I antibody [W6/32]

9

This antibody reacts with a monomorphic epitope of the 45 kD polypeptide, constiituting the HLAA,-B and-C or class I antigen of the human major histocompatibility complex.

For IHC(frozen) a three-step avidin-biotin complex system, a dilution of 1:50 to 1:100 may be used as a guideline. In general, the 0.05M Borate pH 8.0 containing 0.15M Sodium Chloride, 0.05% Sodium Azide, is a good dilutent to use with most antibodies. Optimal dilutions/concentrations should be determined by the researcher.

Flow Cytometry, ImmunoFluorescence, ELISA, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Frozen

Research Use Only

Monoclonal

W6/32

Unconjugated

Mouse

IgG2a

HLA-class I antigens are widely distributed on human nucleated cells. The intensity of HLA-ABC maybe altered in pathological states e.g. malignant cells may loose HLA-ABC, whereas hepatocytes in alcoholic hepatitis, biliary cirrhosis and chronic active hepatitis may show enhanced expression of HLA-ABC.

Human

2°C to 8°C

12352203