HLA-DMA antibody

GeneTex

HLA-DMA antibody

9

WB: 1:500-1:3000. IHC-P: 1:100-1:1000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.

Western Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin

Research Use Only

Polyclonal

1 mg/ml

Unconjugated

HLA-DMA

major histocompatibility complex, class II, DM alpha

D6S222E, DMA, HLADM, RING6, HLA class II histocompatibility antigen, DM alpha chain, MHC class II antigen DMA, class II histocompatibility antigen, M alpha chain, really interesting new gene 6 protein

Rabbit

IgG

HLA class II histocompatibility antigen, DM alpha chain

HLA-DMA belongs to the HLA class II alpha chain paralogues. This class II molecule is a heterodimer consisting of an alpha (DMA) and a beta chain (DMB), both anchored in the membrane. It is located in intracellular vesicles. DM plays a central role in the peptide loading of MHC class II molecules by helping to release the CLIP molecule from the peptide binding site. Class II molecules are expressed in antigen presenting cells (APC: B lymphocytes, dendritic cells, macrophages). The alpha chain is approximately 33-35 kDa and its gene contains 5 exons. Exon one encodes the leader peptide, exons 2 and 3 encode the two extracellular domains, exon 4 encodes the transmembrane domain and the cytoplasmic tail. [provided by RefSeq, Jul 2008]

Human

-20°C or -80°C,2°C to 8°C

41116161