Bio-Connect

HLA-DOA antibody [N1C3]

Research Use Only
GTX114470
GeneTex
ApplicationsFlow Cytometry, Western Blot
Product group Antibodies
ReactivityHuman
TargetHLA-DOA
Sign in to order and to see your custom pricing.
Large volume orders?
Order with a bulk request

Overview

  • Supplier
    GeneTex
  • Product Name
    HLA-DOA antibody [N1C3]
  • Delivery Days Customer
    9
  • Applications
    Flow Cytometry, Western Blot
  • Certification
    Research Use Only
  • Clonality
    Polyclonal
  • Concentration
    0.64 mg/ml
  • Conjugate
    Unconjugated
  • Formulation
    Liquid
  • Gene ID3111
  • Target name
    HLA-DOA
  • Target description
    major histocompatibility complex, class II, DO alpha
  • Target synonyms
    HLA class II histocompatibility antigen, DO alpha chain; HLA-D0-alpha; HLA-DNA; HLADZ; HLA-DZA; lymphocyte antigen; major histocompatibility complex, class II, DN alpha; MHC class II antigen DOA; MHC DN-alpha; MHC DZ alpha
  • Host
    Rabbit
  • Isotype
    IgG
  • Protein IDP06340
  • Protein Name
    HLA class II histocompatibility antigen, DO alpha chain
  • Scientific Description
    HLA-DOA belongs to the HLA class II alpha chain paralogues. HLA-DOA forms a heterodimer with HLA-DOB. The heterodimer, HLA-DO, is found in lysosomes in B cells and regulates HLA-DM-mediated peptide loading on MHC class II molecules. In comparison with classical HLA class II molecules, this gene exhibits very little sequence variation, especially at the protein level. [provided by RefSeq]
  • Reactivity
    Human
  • Storage Instruction
    -20°C or -80°C,2°C to 8°C
  • UNSPSC
    12352203

References

  • Enhanced B Cell Alloantigen Presentation and Its Epigenetic Dysregulation in Liver Transplant Rejection. Ningappa M et al., 2016 Feb, Am J Transplant
    Read more
  • Mapping the HLA-DO/HLA-DM complex by FRET and mutagenesis. Yoon T et al., 2012 Jul 10, Proc Natl Acad Sci U S A
    Read more