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HLA-DOA antibody [N1C3]

GTX114470
GeneTex
ApplicationsFlow Cytometry, Western Blot
Product group Antibodies
ReactivityHuman
TargetHLA-DOA
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Overview

  • Supplier
    GeneTex
  • Product Name
    HLA-DOA antibody [N1C3]
  • Delivery Days Customer
    9
  • Applications
    Flow Cytometry, Western Blot
  • Certification
    Research Use Only
  • Clonality
    Polyclonal
  • Concentration
    0.64 mg/ml
  • Conjugate
    Unconjugated
  • Gene ID3111
  • Target name
    HLA-DOA
  • Target description
    major histocompatibility complex, class II, DO alpha
  • Target synonyms
    HLA-DNA, HLA-DZA, HLADZ, HLA class II histocompatibility antigen, DO alpha chain, HLA-D0-alpha, MHC DN-alpha, MHC DZ alpha, MHC class II antigen DOA, lymphocyte antigen, major histocompatibility complex, class II, DN alpha
  • Host
    Rabbit
  • Isotype
    IgG
  • Protein IDP06340
  • Protein Name
    HLA class II histocompatibility antigen, DO alpha chain
  • Scientific Description
    HLA-DOA belongs to the HLA class II alpha chain paralogues. HLA-DOA forms a heterodimer with HLA-DOB. The heterodimer, HLA-DO, is found in lysosomes in B cells and regulates HLA-DM-mediated peptide loading on MHC class II molecules. In comparison with classical HLA class II molecules, this gene exhibits very little sequence variation, especially at the protein level. [provided by RefSeq]
  • Reactivity
    Human
  • Storage Instruction
    -20°C or -80°C,2°C to 8°C
  • UNSPSC
    12352203

References

  • Ningappa M, Ashokkumar C, Higgs BW, et al. Enhanced B Cell Alloantigen Presentation and Its Epigenetic Dysregulation in Liver Transplant Rejection. Am J Transplant. 2016,16(2):497-508. doi: 10.1111/ajt.13509
    Read this paper
  • Yoon T, Macmillan H, Mortimer SE, et al. Mapping the HLA-DO/HLA-DM complex by FRET and mutagenesis. Proc Natl Acad Sci U S A. 2012,109(28):11276-81. doi: 10.1073/pnas.1113966109
    Read this paper