HLA-DOA antibody [N1C3]
GTX114470
ApplicationsFlow Cytometry, Western Blot
Product group Antibodies
ReactivityHuman
TargetHLA-DOA
Overview
- SupplierGeneTex
- Product NameHLA-DOA antibody [N1C3]
- Delivery Days Customer9
- ApplicationsFlow Cytometry, Western Blot
- CertificationResearch Use Only
- ClonalityPolyclonal
- Concentration0.64 mg/ml
- ConjugateUnconjugated
- Gene ID3111
- Target nameHLA-DOA
- Target descriptionmajor histocompatibility complex, class II, DO alpha
- Target synonymsHLA-DNA, HLA-DZA, HLADZ, HLA class II histocompatibility antigen, DO alpha chain, HLA-D0-alpha, MHC DN-alpha, MHC DZ alpha, MHC class II antigen DOA, lymphocyte antigen, major histocompatibility complex, class II, DN alpha
- HostRabbit
- IsotypeIgG
- Protein IDP06340
- Protein NameHLA class II histocompatibility antigen, DO alpha chain
- Scientific DescriptionHLA-DOA belongs to the HLA class II alpha chain paralogues. HLA-DOA forms a heterodimer with HLA-DOB. The heterodimer, HLA-DO, is found in lysosomes in B cells and regulates HLA-DM-mediated peptide loading on MHC class II molecules. In comparison with classical HLA class II molecules, this gene exhibits very little sequence variation, especially at the protein level. [provided by RefSeq]
- ReactivityHuman
- Storage Instruction-20°C or -80°C,2°C to 8°C
- UNSPSC12352203
References
- Ningappa M, Ashokkumar C, Higgs BW, et al. Enhanced B Cell Alloantigen Presentation and Its Epigenetic Dysregulation in Liver Transplant Rejection. Am J Transplant. 2016,16(2):497-508. doi: 10.1111/ajt.13509Read this paper
- Yoon T, Macmillan H, Mortimer SE, et al. Mapping the HLA-DO/HLA-DM complex by FRET and mutagenesis. Proc Natl Acad Sci U S A. 2012,109(28):11276-81. doi: 10.1073/pnas.1113966109Read this paper





