HLA-DOB antibody

GeneTex

HLA-DOB antibody

9

WB: 1:500-1:2000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.

Western Blot

Research Use Only

Polyclonal

1 mg/ml

Unconjugated

HLA-DOB

major histocompatibility complex, class II, DO beta

DOB; HLA class II histocompatibility antigen, DO beta chain; HLA_DOB; MHC class II antigen DOB

Rabbit

IgG

HLA class II histocompatibility antigen, DO beta chain

HLA-DOB belongs to the HLA class II beta chain paralogues. This class II molecule is a heterodimer consisting of an alpha (DOA) and a beta chain (DOB), both anchored in the membrane. It is located in intracellular vesicles. DO suppresses peptide loading of MHC class II molecules by inhibiting HLA-DM. Class II molecules are expressed in antigen presenting cells (APC: B lymphocytes, dendritic cells, macrophages). The beta chain is approximately 26-28 kDa and its gene contains 6 exons. Exon one encodes the leader peptide, exons 2 and 3 encode the two extracellular domains, exon 4 encodes the transmembrane domain and exon 5 encodes the cytoplasmic tail. [provided by RefSeq, Jul 2008]

-20°C or -80°C,2°C to 8°C

12352203