HLA-DPA1 antibody
GTX104414
ApplicationsImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Frozen, ImmunoHistoChemistry Paraffin
Product group Antibodies
ReactivityHuman, Mouse
TargetHLA-DPA1
Overview
- SupplierGeneTex
- Product NameHLA-DPA1 antibody
- Delivery Days Customer9
- Application Supplier NoteWB: 1:500-1:3000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
- ApplicationsImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Frozen, ImmunoHistoChemistry Paraffin
- CertificationResearch Use Only
- ClonalityPolyclonal
- Concentration1 mg/ml
- ConjugateUnconjugated
- Gene ID3113
- Target nameHLA-DPA1
- Target descriptionmajor histocompatibility complex, class II, DP alpha 1
- Target synonymsDP(W3); DP(W4); DPA1; HLA class II histocompatibility antigen, DP alpha 1 chain; HLA DPA1; HLADP; HLA-DP1A; HLA-DPA; HLA-DPA1*01:03:01:New; HLA-DPA1*02:01:01:NEW; HLA-DPB1; HLASB; HLA-SB alpha chain; MHC class II antigen DP alpha chain; MHC class II DP alpha chain; MHC class II DP3-alpha; MHC class II HLA-DPA1 antigen; MHC class II protein; PLT1
- HostRabbit
- IsotypeIgG
- Protein IDP20036
- Protein NameHLA class II histocompatibility antigen, DP alpha 1 chain
- Scientific DescriptionHLA-DPA1 belongs to the HLA class II alpha chain paralogues. This class II molecule is a heterodimer consisting of an alpha (DPA) and a beta (DPB) chain, both anchored in the membrane. It plays a central role in the immune system by presenting peptides derived from extracellular proteins. Class II molecules are expressed in antigen presenting cells (APC: B lymphocytes, dendritic cells, macrophages). The alpha chain is approximately 33-35 kDa and its gene contains 5 exons. Exon one encodes the leader peptide, exons 2 and 3 encode the two extracellular domains, exon 4 encodes the transmembrane domain and the cytoplasmic tail. Within the DP molecule both the alpha chain and the beta chain contain the polymorphisms specifying the peptide binding specificities, resulting in up to 4 different molecules. [provided by RefSeq]
- ReactivityHuman, Mouse
- Storage Instruction-20°C or -80°C,2°C to 8°C
- UNSPSC12352203
References
- Generation and expression analysis of BAC humanized mice carrying HLA-DP401 haplotype. Li F et al., 2021 Jun, Animal Model Exp MedRead more