HMC-B17 [2935913-83-8]
HY-157838
CAS Number2935913-83-8
Product group Chemicals
Molecular Weight427.54
Overview
- SupplierMedChem Express
- Product NameHMC-B17 [2935913-83-8]
- Delivery Days Customer5
- CAS Number2935913-83-8
- CertificationResearch Use Only
- Molecular FormulaC27H29N3O2
- Molecular Weight427.54
- Scientific DescriptionHMC-B17 is a selective, orally bioavailable HPK1 inhibitor (IC50 = 1.39 nM) that potentiates anti-PD-L1 efficacy. HMC-B17 potently enhances the IL-2 secretion in Jurkat cells (EC50 = 11.56 nM). HMC-B17 can be used for the research of cancer[1].
- SMILESCOC1=C(C=C(C=C1)C2=CNC3=C2C=C(C=N3)C4=CC=C(C=C4)C5CCN(C)CC5)OC
- UNSPSC12352200