HMGA1 blocking peptide

GeneTex

HMGA1 blocking peptide

9

Research Use Only

HMGA1

high mobility group AT-hook 1

HMG-R, HMGA1A, HMGIY, high mobility group protein HMG-I/HMG-Y, high mobility group protein A1, high mobility group protein R, nonhistone chromosomal high-mobility group protein HMG-I/HMG-Y

This gene encodes a non-histone protein involved in many cellular processes, including regulation of inducible gene transcription, integration of retroviruses into chromosomes, and the metastatic progression of cancer cells. The encoded protein preferentially binds to the minor groove of A+T-rich regions in double-stranded DNA. It has little secondary structure in solution but assumes distinct conformations when bound to substrates such as DNA or other proteins. The encoded protein is frequently acetylated and is found in the nucleus. At least seven transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]

-20°C or -80°C,2°C to 8°C

41116100

Human