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HNHA

HNHA

Research Use Only
27206
BPS Bioscience
CAS Number926908-04-5
Product group Chemicals
Estimated Purity≥98%
Molecular Weight303.4 Da
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Overview

  • Supplier
    BPS Bioscience
  • Product Name
    HNHA
  • Delivery Days Customer
    7
  • CAS Number
    926908-04-5
  • Certification
    Research Use Only
  • Estimated Purity
    ≥98%
  • Molecular Formula
    C17H21NO2S
  • Molecular Weight
    303.4 Da
  • Scientific Description
    HNHA is a cell-permeable inhibitor of histone deacetylase (HDAC) activity. HNHA induces histone hyperacetylation and p21 transcription with inhibition of cell cycle progression in human fibrosarcoma HT1080 cells. In in vivo murine xenographs, HNHA is equally as effective as SAHA in inhibiting tumor growth. HNHA inhibits HUVEC growth and prevents tube formation and migration in response to VEGF. Also HNHA blocks retinal neovascularization and choroidal angiogenesis in mice.
  • Storage Instruction
    -20°C
  • UNSPSC
    12352200