HNMT antibody

GeneTex

HNMT antibody

9

WB: 1:500 - 1:2000. IHC-P: 1:50 - 1:200. IP: 1:20 - 1:50. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.

ImmunoPrecipitation, Western Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin

Research Use Only

Polyclonal

Unconjugated

HNMT

histamine N-methyltransferase

histamine N-methyltransferase; HMT; HNMT-S1; HNMT-S2; MRT51

Rabbit

IgG

Histamine N-methyltransferase

In mammals, histamine is metabolized by two major pathways: N(tau)-methylation via histamine N-methyltransferase and oxidative deamination via diamine oxidase. This gene encodes the first enzyme which is found in the cytosol and uses S-adenosyl-L-methionine as the methyl donor. In the mammalian brain, the neurotransmitter activity of histamine is controlled by N(tau)-methylation as diamine oxidase is not found in the central nervous system. A common genetic polymorphism affects the activity levels of this gene product in red blood cells. Multiple alternatively spliced transcript variants that encode different proteins have been found for this gene. [provided by RefSeq, Jul 2008]

Human, Mouse

-20°C or -80°C,2°C to 8°C

12352203