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HNPMI [1980848-48-3]

HY-162148
MedChem Express
CAS Number1980848-48-3
Product group Chemicals
Estimated Purity99.57
Molecular Weight360.41
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Overview

  • Supplier
    MedChem Express
  • Product Name
    HNPMI [1980848-48-3]
  • Delivery Days Customer
    5
  • CAS Number
    1980848-48-3
  • Certification
    Research Use Only
  • Estimated Purity
    99.57
  • Molecular Formula
    C22H20N2O3
  • Molecular Weight
    360.41
  • Scientific Description
    HNPMI is an inhibitor of EGFR and has cytotoxic effects on tumor cells. HNPMI can downregulate the protein levels of osteopontin, survivin and cathepsin S, leading to apoptosis. HNPMI also regulates BCL-2/BAX and p53 in CRC cell lines to inhibit tumorigenesis[1].
  • SMILES
    CC1=CC=C(C(N2CCC3=C2C=CC=C3)C4=CC([N+]([O-])=O)=CC=C4O)C=C1
  • Storage Instruction
    2°C to 8°C
  • UNSPSC
    12352200