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Homoharringtonine [26833-87-4]

Homoharringtonine [26833-87-4]

T3380
TargetMol Chemicals
CAS Number26833-87-4
Product group Chemicals
Estimated Purity98.59%
Molecular Weight545.62
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Overview

  • Supplier
    TargetMol Chemicals
  • Product Name
    Homoharringtonine [26833-87-4]
  • Delivery Days Customer
    4
  • CAS Number
    26833-87-4
  • Certification
    Research Use Only
  • Chemical Name
    Homoharringtonine
  • Estimated Purity
    98.59%
  • Molecular Formula
    C29H39NO9
  • Molecular Weight
    545.62
  • Scientific Description
    Homoharringtonine (HHT) is a natural alkaloid that inhibits the translation of proteins and is cytotoxic. Homoharringtonine acts on the ribosomes of tumor cells to inhibit the elongation step of protein translation, thereby inhibiting protein synthesis, and has antitumor activity.
  • Shelf life instruction
    3 years
  • SMILES
    COC(=O)CC(O)(CCCC(C)(C)O)C(=O)OC1C2c3cc4OCOc4cc3CCN3CCCC23C=C1OC
  • Storage Instruction
    -20°C
  • UNSPSC
    12352200

References

  • Cao W, Liu Y, Zhang R, et al. Homoharringtonine induces apoptosis and inhibits STAT3 via IL-6/JAK1/STAT3 signal pathway in Gefitinib-resistant lung cancer cells. Sci Rep. 2015,5:8477. doi: 10.1038/srep08477
    Read this paper