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ProductsBack/HORMAD2 Antibody

Immunohistochemistry of paraffin-embedded human testis tissue using CSB-PA836683LA01HU at dilution of 1:100

Immunohistochemistry of paraffin-embedded human testis tissue using CSB-PA836683LA01HU at dilution of 1:100

Immunohistochemistry of paraffin-embedded human testis tissue using CSB-PA836683LA01HU at dilution of 1:100

HORMAD2 Antibody

CSB-PA836683LA01HU

ApplicationsELISA, ImmunoHistoChemistry

Product group Antibodies

ReactivityHuman

TargetHORMAD2

Overview

Supplier
Cusabio
Product Name
HORMAD2 Antibody
Delivery Days Customer
20
Applications
ELISA, ImmunoHistoChemistry
Certification
Research Use Only
Clonality
Polyclonal
Conjugate
Unconjugated
Gene ID150280
Target name
HORMAD2
Target description
HORMA domain containing 2
Target synonyms
CT46.2, HORMA domain-containing protein 2
Host
Rabbit
Isotype
IgG
Protein IDQ8N7B1
Protein Name
HORMA domain-containing protein 2
Scientific Description
Essential for synapsis surveillance during meiotic prophase via the recruitment of ATR activity. Plays a key role in the male mid-pachytene checkpoint and the female meiotic prophase checkpoint: required for efficient build-up of ATR activity on unsynapsed chromosome regions, a process believed to form the basis of meiotic silencing of unsynapsed chromatin (MSUC) and meiotic prophase quality control in both sexes. Required for the DNA double-strand break-independent, BRCA1-dependent activation of ATR on the sex chromosomes that is essential for normal sex body formation.
Reactivity
Human
Storage Instruction
-20°C or -80°C
UNSPSC
41116161

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