HPGDS inhibitor 1

MedChem Express

HPGDS inhibitor 1 [1033836-12-2]

5

1033836-12-2

Research Use Only

99.04

C19H19F4N3O

381.37

HPGDS inhibitor 1 is a potent, selective and orally active Hematopoietic Prostaglandin D Synthase (HPGDS) inhibitor with an IC 50 s of 0.6 nM and 32 nM in enzyme and cellular assays, respectively. HPGDS inhibitor 1 does not inhibit human L-PGDS, mPGES, COX-1, COX-2, or 5-LOX [1] .

O=C(NC1CCN(CC(F)(F)F)CC1)C2=CC=C(C3=CC=CC(F)=C3)N=C2

-20°C,2°C to 8°C

12352200