HPK1-IN-2 [2056122-11-1]

TargetMol Chemicals

HPK1-IN-2 [2056122-11-1]

4

Chemical

Research Use Only

HPK1-IN-2

99.62%

C19H20N6OS

380.47

HPK1-IN-2 (Thieno[2,3-b]pyridin-6(7H)-one, 4-amino-5-[6-(4-methyl-1-piperazinyl)-1H-benzimidazol-2-yl]-HPK1-IN-2) is a potent and orally active inhibitor of hematopoietic progenitor kinase-1 (HPK1; IC50<0.05 micromicro). It also inhibits Lck (0.05 micromicro<IC50<0.5 micromicro) and Flt3 (IC50<0.05 micromicro) kinase activities with antitumor activity.

3 years

NC1=C(C=2NC=3C(N2)=CC=C(C3)N4CCN(C)CC4)C(=O)NC5=C1C=CS5

-20°C

51202000