HPK1-IN-2 dihydrochloride [2375595-72-3]

TargetMol Chemicals

HPK1-IN-2 dihydrochloride [2375595-72-3]

16

Chemical

Research Use Only

HPK1-IN-2 dihydrochloride

C19H22Cl2N6OS

453.39

HPK1-IN-2 dihydrochloride, a potent and orally active inhibitor of hematopoietic progenitor kinase-1 (HPK1) with an IC 50 of less than 0.05 microM, demonstrates significant antitumor activity. It additionally exhibits inhibition of Lck kinase activity, with an IC 50 ranging from 0.05 to less than 0.5 microM, and Flt3 kinase activity, with an IC 50 of less than 0.05 microM [1].

3 years

NC1=C(C=2NC=3C(N2)=CC=C(C3)N4CCN(C)CC4)C(=O)NC5=C1C=CS5.Cl

-20°C

51202000