HPK1-IN-45

MedChem Express

HPK1-IN-45

5

Research Use Only

C30H29N5O3

507.58

HPK1-IN-45 (Compound 3) is a HPK1 inhibitor, with an IC50 of 0.3 nM. HPK1-IN-45 inhibits SLP-76 phosphorylation (IC50 = 57.52 nM) and IL-2 release (IC50 = 38 nM). HPK1-IN-45 can be used for the research of cancer[1].

CC1(C2=CC(N3CCOCC3)=CC=C2NC4=C1C=C(C5=C4C(NC=C5)=O)C6=CN=C7C(OC)=CC=CN67)C

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