HPK1-IN-55

MedChem Express

HPK1-IN-55

5

Research Use Only

C30H34N8O3

554.64

HPK1-IN-55 (compound 19) is a selective and orally active hematopoietic progenitor kinase 1 (HPK1) inhibitor with an IC50 of 637-fold vs GCK-like kinase and >1022-fold vs LCK). HPK1-IN-55 has anticancer effects[1].

COC1=CC(NC2=CC=C3C4(N(CC3=N2)C)CCN(CC4)C5COC5)=C(N=C1C6=C(C7=CC=C6)N=CN7C)C(N)=O

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