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HPOB [1429651-50-2]

Research Use Only
HY-19747
MedChem Express
CAS Number1429651-50-2
Product group Chemicals
Estimated Purity99.80
Molecular Weight314.34
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Overview

  • Supplier
    MedChem Express
  • Product Name
    HPOB [1429651-50-2]
  • Delivery Days Customer
    10
  • CAS Number
    1429651-50-2
  • Certification
    Research Use Only
  • Estimated Purity
    99.80
  • Molecular Formula
    C17H18N2O4
  • Molecular Weight
    314.34
  • Scientific Description
    HPOB is a highly potent and selective inhibitor of HDAC6 with an IC50 of 56 nM. HPOB displays >30 fold less potent against other HDACs. HPOB enhances the effectiveness of DNA-damaging anticancer agents in transformed cells but not normal cells. HPOB does not block the ubiquitin-binding activity of HDAC6[1].
  • SMILES
    O=C(N(CCO)C1=CC=CC=C1)CC2=CC=C(C(NO)=O)C=C2
  • Storage Instruction
    -20°C,2°C to 8°C
  • UNSPSC
    12352200