HPOB

MedChem Express

HPOB [1429651-50-2]

10

1429651-50-2

Research Use Only

99.80

C17H18N2O4

314.34

HPOB is a highly potent and selective inhibitor of HDAC6 with an IC 50 of 56 nM. HPOB displays >30 fold less potent against other HDACs. HPOB enhances the effectiveness of DNA-damaging anticancer agents in transformed cells but not normal cells. HPOB does not block the ubiquitin-binding activity of HDAC6 [1] .

O=C(N(CCO)C1=CC=CC=C1)CC2=CC=C(C(NO)=O)C=C2

-20°C,2°C to 8°C

12352200