ProductsBack/HPS2 antibody [N1N2], N-term

HPS2 antibody [N1N2], N-term

Name: HPS2 antibody [N1N2], N-term
SKU: GTX113878_G10
Availability: BackOrder

GTX113878

ApplicationsWestern Blot

Product group Antibodies

ReactivityMouse

TargetAP3B1

Overview

Supplier
GeneTex
Product Name
HPS2 antibody [N1N2], N-term
Delivery Days Customer
9
Application Supplier Note
WB: 1:500-1:3000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
Applications
Western Blot
Certification
Research Use Only
Clonality
Polyclonal
Concentration
0.49 mg/ml
Conjugate
Unconjugated
Gene ID8546
Target name
AP3B1
Target description
adaptor related protein complex 3 subunit beta 1
Target synonyms
adaptor protein complex AP-3 subunit beta-1; adaptor related protein complex 3 beta 1 subunit; ADTB3; ADTB3A; AP-3 complex beta-3A subunit; AP-3 complex subunit beta-1; beta-3A; beta-3A-adaptin; clathrin assembly protein complex 3 beta-1 large chain; HPS; HPS2; PE
Host
Rabbit
Isotype
IgG
Protein IDO00203
Protein Name
AP-3 complex subunit beta-1
Scientific Description
This gene encodes a protein that may play a role in organelle biogenesis associated with melanosomes, platelet dense granules, and lysosomes. The encoded protein is part of the heterotetrameric AP-3 protein complex which interacts with the scaffolding protein clathrin. Mutations in this gene are associated with Hermansky-Pudlak syndrome type 2. [provided by RefSeq]
Reactivity
Mouse
Storage Instruction
-20°C or -80°C,2°C to 8°C
UNSPSC
12352203

AP-3-dependent targeting of flippase ATP8A1 to lamellar bodies suppresses activation of YAP in alveolar epithelial type 2 cells. Kook S et al., 2021 May 18, Proc Natl Acad Sci U S A
Read more
Gene-edited MLE-15 Cells as a Model for the Hermansky-Pudlak Syndromes. Kook S et al., 2018 May, Am J Respir Cell Mol Biol
Read more