HPS2 antibody [N1N2], N-term
GTX113878
ApplicationsWestern Blot
Product group Antibodies
TargetAP3B1
Overview
- SupplierGeneTex
- Product NameHPS2 antibody [N1N2], N-term
- Delivery Days Customer9
- Application Supplier NoteWB: 1:500-1:3000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
- ApplicationsWestern Blot
- CertificationResearch Use Only
- ClonalityPolyclonal
- Concentration0.49 mg/ml
- ConjugateUnconjugated
- Gene ID8546
- Target nameAP3B1
- Target descriptionadaptor related protein complex 3 subunit beta 1
- Target synonymsADTB3, ADTB3A, HPS, HPS2, PE, AP-3 complex subunit beta-1, AP-3 complex beta-3A subunit, adaptor protein complex AP-3 subunit beta-1, adaptor related protein complex 3 beta 1 subunit, beta-3A, beta-3A-adaptin, clathrin assembly protein complex 3 beta-1 large chain
- HostRabbit
- IsotypeIgG
- Protein IDO00203
- Protein NameAP-3 complex subunit beta-1
- Scientific DescriptionThis gene encodes a protein that may play a role in organelle biogenesis associated with melanosomes, platelet dense granules, and lysosomes. The encoded protein is part of the heterotetrameric AP-3 protein complex which interacts with the scaffolding protein clathrin. Mutations in this gene are associated with Hermansky-Pudlak syndrome type 2. [provided by RefSeq]
- Storage Instruction-20°C or -80°C,2°C to 8°C
- UNSPSC12352203
References
- Kook S, Wang P, Meng S, et al. AP-3-dependent targeting of flippase ATP8A1 to lamellar bodies suppresses activation of YAP in alveolar epithelial type 2 cells. Proc Natl Acad Sci U S A. 2021,118(20). doi: 10.1073/pnas.2025208118Read this paper
- Kook S, Qi A, Wang P, et al. Gene-edited MLE-15 Cells as a Model for the Hermansky-Pudlak Syndromes. Am J Respir Cell Mol Biol. 2018,58(5):566-574. doi: 10.1165/rcmb.2017-0324MARead this paper





