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HPS2 antibody [N1N2], N-term

GTX113878
GeneTex
ApplicationsWestern Blot
Product group Antibodies
TargetAP3B1
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Overview

  • Supplier
    GeneTex
  • Product Name
    HPS2 antibody [N1N2], N-term
  • Delivery Days Customer
    9
  • Application Supplier Note
    WB: 1:500-1:3000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
  • Applications
    Western Blot
  • Certification
    Research Use Only
  • Clonality
    Polyclonal
  • Concentration
    0.49 mg/ml
  • Conjugate
    Unconjugated
  • Gene ID8546
  • Target name
    AP3B1
  • Target description
    adaptor related protein complex 3 subunit beta 1
  • Target synonyms
    ADTB3, ADTB3A, HPS, HPS2, PE, AP-3 complex subunit beta-1, AP-3 complex beta-3A subunit, adaptor protein complex AP-3 subunit beta-1, adaptor related protein complex 3 beta 1 subunit, beta-3A, beta-3A-adaptin, clathrin assembly protein complex 3 beta-1 large chain
  • Host
    Rabbit
  • Isotype
    IgG
  • Protein IDO00203
  • Protein Name
    AP-3 complex subunit beta-1
  • Scientific Description
    This gene encodes a protein that may play a role in organelle biogenesis associated with melanosomes, platelet dense granules, and lysosomes. The encoded protein is part of the heterotetrameric AP-3 protein complex which interacts with the scaffolding protein clathrin. Mutations in this gene are associated with Hermansky-Pudlak syndrome type 2. [provided by RefSeq]
  • Storage Instruction
    -20°C or -80°C,2°C to 8°C
  • UNSPSC
    12352203

References

  • Kook S, Wang P, Meng S, et al. AP-3-dependent targeting of flippase ATP8A1 to lamellar bodies suppresses activation of YAP in alveolar epithelial type 2 cells. Proc Natl Acad Sci U S A. 2021,118(20). doi: 10.1073/pnas.2025208118
    Read this paper
  • Kook S, Qi A, Wang P, et al. Gene-edited MLE-15 Cells as a Model for the Hermansky-Pudlak Syndromes. Am J Respir Cell Mol Biol. 2018,58(5):566-574. doi: 10.1165/rcmb.2017-0324MA
    Read this paper