Bio-Connect

HRE Luciferase Reporter ME-180 Cell Line

82436
BPS Bioscience
CategoryCell Culture
Product group Cell Culture
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Overview

  • Supplier
    BPS Bioscience
  • Product Name
    HRE Luciferase Reporter ME-180 Cell Line
  • Delivery Days Customer
    23
  • Certification
    Research Use Only
  • Scientific Description
    HRE Luciferase Reporter ME-180 Cell Line is designed to monitor the activity of hypoxia-inducible factors (HIFs). It contains a firefly luciferase reporter driven by multiple copies of hypoxia response element (HRE) located upstream of the minimal TATA promoter. As oxygen becomes rate limiting, HIFs form heterodimers that recognize cognate HREs, inducing transcription of the luciferase reporter. The cell line has been functionally validated in response to the hypoxia-mimetics cobalt chloride (CoCl2) and Deferoxamine (DFO). Interested in screening and profiling inhibitors, blocking antibodies, or activators without the need to purchase and license the cell line? Check out our Cell Signaling Pathway Screening.
  • Storage Instruction
    Liquid Nitrogen
  • UNSPSC
    12352207