HRX-0233
ORB2279904
Molecular Weight497.52
Product group Chemicals
Overview
- SupplierBiorbyt
- Product NameHRX-0233
- Delivery Days Customer10
- CertificationResearch Use Only
- Molecular FormulaC24H21F2N5O3S
- Molecular Weight497.52
- Scientific DescriptionHRX-0233 (HRX0233) is a potent and selective inhibitor of MAP2K4 (MKK4), a kinase involved in the stress-activated protein kinase (SAPK) signaling pathway. MAP2K4 plays a role in regulating cellular responses to stress, apoptosis, and tumorigenesis. HRX-0233 has shown particular promise in KRAS-mutant cancers, where it exhibits synergistic effects with RAS inhibitors, making it a potential candidate for combination therapy in these difficult-to-treat cancers.
- UNSPSC12352200