HS3ST3B1 antibody, N-term

GeneTex

HS3ST3B1 antibody, N-term

9

WB: 0.2-2.5 ug/ml. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.

Western Blot

Research Use Only

Polyclonal

0.5-1 mg/ml

Unconjugated

HS3ST3B1

heparan sulfate-glucosamine 3-sulfotransferase 3B1

3-OST-3B, 3OST3B1, h3-OST-3B, heparan sulfate glucosamine 3-O-sulfotransferase 3B1, heparan sulfate (glucosamine) 3-O-sulfotransferase 3B1, heparan sulfate 3-O-sulfotransferase 3B1, heparan sulfate D-glucosaminyl 3-O-sulfotransferase 3B1

Rabbit

IgG

Heparan sulfate glucosamine 3-O-sulfotransferase 3B1

The protein encoded by this gene is a type II integral membrane protein that belongs to the 3-O-sulfotransferases family. These proteins catalyze the addition of sulfate groups at the 3-OH position of glucosamine in heparan sulfate. The substrate specificity of individual members of the family is based on prior modification of the heparan sulfate chain, thus allowing different members of the family to generate binding sites for different proteins on the same heparan sulfate chain. Following treatment with a histone deacetylase inhibitor, expression of this gene is activated in a pancreatic cell line. The increased expression results in promotion of the epithelial-mesenchymal transition. In addition, the modification catalyzed by this protein allows herpes simplex virus membrane fusion and penetration. A very closely related homolog with an almost identical sulfotransferase domain maps less than 1 Mb away. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2014]

Human

-20°C or -80°C,2°C to 8°C

12352203