Inhibition of FcRn:HSA binding by the antibody ADM31.
Inhibition of FcRn:HSA binding by the antibody ADM31.
HSA:FcRn Neutralizing Antibody Screening Chemiluminescence Assay Kit
82151
Product group Assays
Overview
- SupplierBPS Bioscience
- Product NameHSA:FcRn Neutralizing Antibody Screening Chemiluminescence Assay Kit
- Delivery Days Customer7
- ApplicationsNeutralisation/Blocking
- CertificationResearch Use Only
- Scientific DescriptionThe FcRn:HSA Binding Chemiluminescent Assay Kit is designed for screening and profiling neutralizing antibodies or blockers of the interaction between Human Serum Albumin (HSA) and human FcRn. This kit comes in a convenient 384-well format, with Biotinylated HSA and FcRn (FCGRT/B2M) (amino acids 24-297 of FCGRT and 21-119 of B2M), Streptavidin-HRP, and assay buffers for 400 reactions. The assay requires only a few steps. First, FcRn is coated on a 384-well plate overnight. After blocking, the protein is pre-incubated with the neutralizing antibody or blocker. Upon subsequent incubation with Biotin-HSA, the plate is treated with Streptavidin-HRP followed by addition of an HRP substrate to produce chemiluminescence, which can then be measured using a chemiluminescence reader.
- Storage InstructionSee manual
- UNSPSC41116133